Rapid Single-Round Pool Testing of Infectious Disease Enabled by Multicolor Digital Melting PCR.
Sign Up to like & getrecommendations! Published in 2023 at "Small"
DOI: 10.1002/smll.202205636
Abstract: Pooled nucleic acid amplification test is a promising strategy to reduce cost and resources for screening large populations for infectious disease. However, the benefit of pooled testing is reversed when disease prevalence is high, because… read more here.
Keywords: multicolor digital; disease; single round; pcr ... See more keywords
INSTIs and NNRTIs Potently Inhibit HIV-1 Polypurine Tract Mutants in a Single Round Infection Assay
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DOI: 10.3390/v13122501
Abstract: Integrase strand transfer inhibitors (INSTIs) are a class of antiretroviral compounds that prevent the insertion of a DNA copy of the viral genome into the host genome by targeting the viral enzyme integrase (IN). Dolutegravir… read more here.
Keywords: single round; instis nnrtis; polypurine tract; hiv polypurine ... See more keywords
A Single-Round Infection Fluorescent SARS-CoV-2 Neutralization Test for COVID-19 Serological Testing at a Biosafety Level-2 Laboratory
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DOI: 10.3390/v14061211
Abstract: A robust serological test to measure neutralizing antibodies against SARS-CoV-2 in biosafety level-2 (BSL-2) laboratories is useful for monitoring antibody response after vaccination or natural infection. The gold standard assay is the conventional plaque reduction… read more here.
Keywords: biosafety level; infection; neutralization test; test ... See more keywords
Single-Round Infectious Particle Antiviral Screening Assays for the Japanese Encephalitis Virus
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DOI: 10.3390/v9040076
Abstract: Japanese Encephalitis virus (JEV) is a mosquito-borne flavivirus with a positive-sense single-stranded RNA genome that contains a big open reading frame (ORF) flanked by 5′- and 3′- untranslated regions (UTRs). Nearly 30,000 JE cases with… read more here.
Keywords: encephalitis virus; jev; japanese encephalitis; jev egfp ... See more keywords