The Effects of Clarithromycin on the Pharmacokinetics of Apixaban in Healthy Volunteers: A Single-Sequence Crossover Study
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DOI: 10.1007/s40256-019-00348-2
Abstract: BackgroundThis was an open-label, phase I, nonrandomized, single-sequence, crossover study to evaluate the effect of concomitant administration of multiple doses of clarithromycin on the single-dose exposure, safety, and tolerability of apixaban in healthy subjects.MethodsIn total,… read more here.
Keywords: sequence crossover; administration; single sequence; clarithromycin ... See more keywords
A Track-Based Molecular Synthesizer that Builds a Single-Sequence Oligomer through Iterative Carbon-Carbon Bond Formation
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DOI: 10.1016/j.chempr.2020.09.021
Abstract: Summary We report an artificial molecular machine that moves along a track, iteratively joining building blocks to form an oligomer of single sequence with a continuous backbone of carbon-carbon bonds. The rotaxane features a macrocycle… read more here.
Keywords: carbon; single sequence; track; carbon carbon ... See more keywords