Single serine on TSC2 exerts biased control over mTORC1 activation mediated by ERK1/2 but not Akt
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DOI: 10.26508/lsa.202101169
Abstract: Both ERK1/2 and Akt kinases activate mTORC1, but only the former is bidirectionally regulated by the status of serine S1364 on TSC2 that confers input-selective mTORC1 amplification or attenuation. read more here.
Keywords: tsc2; akt; single serine; mtorc1 ... See more keywords