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Published in 2018 at "Bioinformatics"
DOI: 10.1093/bioinformatics/bty569
Abstract: Motivation Single amino acid variations (SAVs) in proteināprotein interaction (PPI) sites play critical roles in diseases. PPI sites (interfaces) have a small subset of residues called hot spots that contribute significantly to the binding energy,…
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Keywords:
amino acid;
acid variations;
protein protein;
singlet hot ... See more keywords