Design and synthesis of sinomenine isoxazole derivatives via 1,3-dipolar cycloaddition reaction
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DOI: 10.1080/14786419.2019.1677649
Abstract: Abstract A novel structure of sinomenine isoxazole derivatives is synthesised from sinomenine hydrochloride and aromatic aldehydes and requires six steps. 19 target compounds have been obtained in good yields. The sinomenine hydrochloride transforms to 4-alkynyl… read more here.
Keywords: isoxazole derivatives; reaction; sinomenine isoxazole; dipolar cycloaddition ... See more keywords