Treatment of Sindbis Virus-Infected Neurons with Antibody to E2 Alters Synthesis of Complete and nsP1-Expressing Defective Viral RNAs
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DOI: 10.1128/mbio.02221-22
Abstract: Alphaviruses are important causes of viral encephalomyelitis without approved treatments or vaccines. Antibody to the Sindbis virus (SINV) E2 glycoprotein is required for immune-mediated noncytolytic virus clearance from neurons. ABSTRACT Alphaviruses are positive-sense RNA viruses… read more here.
Keywords: dvg; rna; sindbis virus; sinv ... See more keywords
Cross-utilisation of template RNAs by alphavirus replicases
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DOI: 10.1371/journal.ppat.1008825
Abstract: Most alphaviruses (family Togaviridae) including Sindbis virus (SINV) and other human pathogens, are transmitted by arthropods. The first open reading frame in their positive strand RNA genome encodes for the non-structural polyprotein, a precursor to… read more here.
Keywords: utilisation template; alphavirus replicases; template; sinv ... See more keywords
Presence of Antibodies against Sindbis Virus in the Israeli Population: A Nationwide Cross-Sectional Study
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DOI: 10.3390/v11060542
Abstract: Sindbis virus (SINV) is a mosquito-borne alphavirus circulating globally. SINV outbreaks have been mainly reported in North-European countries. In Israel, SINV was detected in 6.3% of mosquito pools; however, SINV infection in humans has rarely… read more here.
Keywords: sinv; sindbis virus; sinv igg; israeli population ... See more keywords