The Yeast Heterochromatin Protein Sir3 Experienced Functional Changes in the AAA+ Domain After Gene Duplication and Subfunctionalization
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DOI: 10.1534/genetics.117.300180
Abstract: A key unresolved issue in molecular evolution is how paralogs diverge after gene duplication. For multifunctional genes, duplication is often followed by subfunctionalization. Subsequently, new or optimized molecular properties may evolve once the protein is… read more here.
Keywords: protein; sir3; duplication; gene duplication ... See more keywords