Co-Delivery of siRNA and Chemotherapeutic Drug Using 2C5 Antibody-Targeted Dendrimer-Based Mixed Micelles for Multidrug Resistant Cancers
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DOI: 10.3390/pharmaceutics14071470
Abstract: Multidrug resistance (MDR) observed in tumors significantly hinders the efficacy of chemotherapy. Downregulation of efflux proteins, such as P-glycoprotein (P-gp), using small interfering RNA (siRNA) can be an effective way to minimize the resistance in… read more here.
Keywords: dendrimer; delivery sirna; sirna chemotherapeutic; drug ... See more keywords