Novel Chitosan Derivatives with Reversible Cationization and Hydrophobicization for Tumor Cytoplasm-Specific Burst Co-delivery of siRNA and Chemotherapeutics.
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DOI: 10.1021/acsami.9b19373
Abstract: Despite the great potential of combination therapy based on siRNA and chemotherapeutics, an efficient vehicle with abilities of well drug co-loading, synchronizing in vivo trafficking and target-specific co-burst release remains elusive, which results in a… read more here.
Keywords: novel chitosan; reversible cationization; specific burst; cationization hydrophobicization ... See more keywords