Folate receptor-directed orthogonal click-functionalization of siRNA lipopolyplexes for tumor cell killing in vivo.
Sign Up to like & getrecommendations! Published in 2018 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2018.03.031
Abstract: The delivery of small interfering RNA (siRNA) and its therapeutic usage as an anti-cancer agent requires a carrier system for selective internalization into the cytosol of tumor cells. We prepared folate-bearing formulations by first complexing… read more here.
Keywords: sirna lipopolyplexes; folate receptor; functionalization; sirna ... See more keywords