Lipid-siRNA Organization Modulates the Intracellular Dynamics of Lipid Nanoparticles
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DOI: 10.1021/jacs.4c18308
Abstract: Lipid nanoparticles (LNPs) are widely used for delivering therapeutic nucleic acids, yet the relationship between their internal structure and intracellular behavior, particularly before RNA release, remains unclear. Here, we elucidate how lipid-siRNA organization within LNPs… read more here.
Keywords: sirna organization; intracellular dynamics; organization modulates; lipid sirna ... See more keywords