Control of dengue virus in the midgut of Aedes aegypti by ectopic expression of the dsRNA-binding protein Loqs2
Sign Up to like & getrecommendations! Published in 2018 at "Nature Microbiology"
DOI: 10.1038/s41564-018-0268-6
Abstract: Dengue virus (DENV) is an arbovirus transmitted to humans by Aedes mosquitoes1. In the insect vector, the small interfering RNA (siRNA) pathway is an important antiviral mechanism against DENV2–5. However, it remains unclear when and… read more here.
Keywords: dengue virus; midgut; expression; sirna pathway ... See more keywords
aBravo Is a Novel Aedes aegypti Antiviral Protein That Interacts with, but Acts Independently of, the Exogenous siRNA Pathway Effector Dicer 2
Sign Up to like & getrecommendations! Published in 2020 at "Viruses"
DOI: 10.3390/v12070748
Abstract: Mosquitoes, such as Aedes aegypti, can transmit arboviruses to humans. The exogenous short interfering RNA (exo-siRNA) pathway plays a major antiviral role in controlling virus infection in mosquito cells. The Dicer 2 (Dcr2) nuclease is… read more here.
Keywords: protein; aedes aegypti; antiviral protein; rna ... See more keywords