Intestinal Dysbiosis Correlates With Sirolimus-Induced Metabolic Disorders in Mice.
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DOI: 10.1097/tp.0000000000003494
Abstract: BACKGROUND Long-time use of pharmacological immunosuppressive agents frequently leads to metabolic disorders. Most studies have focused on islet toxicity leading to post-transplantation diabetes mellitus. In contrast, the link between intestinal dysbiosis and immunosuppressive drug-induced metabolic… read more here.
Keywords: sirolimus induced; systemic inflammation; metabolic disorders; induced metabolic ... See more keywords