Serum Sirolimus Levels After Implantation of Third Generation Drug Eluting Cobalt Chromium Coronary Stent in Ductus Arteriosus in Neonates with Duct-Dependent Pulmonary Circulation
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DOI: 10.1007/s00246-020-02381-4
Abstract: Ductal stenting (DS) palliates duct-dependent lesions using coronary stents. Sirolimus-eluting stents have replaced bare-metal stents in coronary interventions. Concerns exist about sirolimus levels in neonates. Therapeutic immunosuppressive sirolimus level is 5–15 ng/ml. After neonatal DS, drug… read more here.
Keywords: sirolimus levels; drug; sirolimus eluting; stent ... See more keywords
Safety of drug-eluting stents for stenting patent arterial duct in neonates.
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DOI: 10.1017/s104795112200110x
Abstract: OBJECTIVES The primary objective was to evaluate the trend of blood sirolimus concentrations in neonates following ductal stenting. The long-term outcomes and incidence of infections were also evaluated. METHODS Prospective open-label observational study in a… read more here.
Keywords: sirolimus levels; drug eluting; eluting stents; ductal stenting ... See more keywords