Discovery of high affinity, pan-allelic, and pan-mammalian reactive antibodies against the myeloid checkpoint receptor SIRPα
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DOI: 10.1080/19420862.2019.1624123
Abstract: ABSTRACT Targeting the CD47-signal-regulatory protein α (SIRPα) pathway represents a novel therapeutic approach to enhance anti-cancer immunity by promoting both innate and adaptive immune responses. Unlike CD47, which is expressed ubiquitously, SIRPα expression is mainly… read more here.
Keywords: allelic pan; anti sirp; sirp antibodies; sirp ... See more keywords