A SIRPαFc Fusion Protein Conjugated With the Collagen-Binding Domain for Targeted Immunotherapy of Non-Small Cell Lung Cancer
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DOI: 10.3389/fimmu.2022.845217
Abstract: The SIRPαFc fusion protein can block the immunosuppressive CD47-SIRPα signal between macrophages and tumor cells as a decoy receptor and has demonstrated its immunotherapeutic efficacy in various tumors. However, its clinical application was limited because… read more here.
Keywords: fusion protein; sirp fusion; collagen binding; sirp ... See more keywords