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Targeting of SIRPα as a potential therapy for Langerhans cell histiocytosis

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2 Published in 2023 at "Cancer Science"

DOI: 10.1111/cas.15758

Abstract: Langerhans cell histiocytosis (LCH) is a rare neoplastic disorder characterized by inflammatory lesions arising from the anomalous accumulation of pathogenic CD1a+CD207+ dendritic cells (DCs). SIRPα is a transmembrane protein highly expressed in myeloid cells such… read more here.

Keywords: cd11c; langerhans cell; lch; cell histiocytosis ... See more keywords