A human antibody specific for SIRPĪ± reprograms macrophages and promotes antibody mediated anti-cancer activity
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DOI: 10.1371/journal.pone.0321169
Abstract: Several T cell immune checkpoint blockade therapies have shown initial successes in multiple cancers. However, significant issues remain, including tumor relapse, severe toxicities, and a lack of efficacy in most patients. SIRPĪ±, commonly known as… read more here.
Keywords: antibody; sirp reprograms; antibody specific; specific sirp ... See more keywords