Genetic Control of Splicing at SIRPG Modulates Risk of Type 1 Diabetes.
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DOI: 10.2337/db21-0194
Abstract: Signal regulatory protein SIRPĪ³ (CD172G) is expressed on the surface of lymphocytes where it acts by engaging its ligand, CD47. SIRPG, which encodes SIRPĪ³, contains a non-synonymous coding variant, rs6043409, which is significantly associated with… read more here.
Keywords: risk type; transcript isoforms; type diabetes; sirpg ... See more keywords