Downregulated SIRT1 in the CeA is involved in chronic pain-depression comorbidity
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DOI: 10.1016/j.brainresbull.2021.07.002
Abstract: Comorbid chronic pain and depression are increasingly becoming a concerning public problem, but the underlying mechanisms remain unclear. Here, we demonstrate that pain-related depression-like behaviors are induced in a rat model of chronic constriction injury… read more here.
Keywords: depression; sirt1 cea; pain depression; chronic pain ... See more keywords