Astaxanthin attenuates contrast agent-induced acute kidney injury in vitro and in vivo via the regulation of SIRT1/FOXO3a expression
Sign Up to like & getrecommendations! Published in 2018 at "International Urology and Nephrology"
DOI: 10.1007/s11255-018-1788-y
Abstract: PurposeThe study was processed to investigate the effect of astaxanthin (AST; 3,3-dihydroxybeta, beta-carotene-4,4-dione) on the acute kidney injury induced by iohexol and the relationship with SIRT1/FOXO3a signal pathway.MethodsThirty male Sprague Dawley rats were randomly divided… read more here.
Keywords: sirt1; sirt1 foxo3a; group; acute kidney ... See more keywords
Resveratrol attenuates radiation enteritis through the SIRT1/FOXO3a and PI3K/AKT signaling pathways.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.03.122
Abstract: Radiation enteritis (RE) is the most common radiotherapy complication, and effective RE treatments are lacking. Resveratrol exerts beneficial effects on radiation injury. However, the effect of resveratrol in radiation-induced intestinal injury and the underlying mechanism… read more here.
Keywords: sirt1; sirt1 foxo3a; foxo3a pi3k; radiation induced ... See more keywords
CYP2J2-produced epoxyeicosatrienoic acids attenuate ischemia/reperfusion-induced acute kidney injury by activating the SIRT1-FoxO3a pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.117327
Abstract: Cytochrome P450 (CYP) epoxygenases can metabolize arachidonic acids to epoxyeicosatrienoic acids (EETs), which play a protective role in the renal system, but their involvement in ischemia/reperfusion (I/R)-induced acute kidney injury remains unknown. Here, using a… read more here.
Keywords: sirt1 foxo3a; kidney injury; epoxyeicosatrienoic acids; cyp2j2 ... See more keywords
Cx43-Delivered miR-181b Negatively Regulates Sirt1/FOXO3a Signalling Pathway-Mediated Apoptosis on Intestinal Injury in Sepsis.
Sign Up to like & getrecommendations! Published in 2023 at "Digestion"
DOI: 10.1159/000529102
Abstract: INTRODUCTION Gap junctions can transmit signals between cells, including miRNAs, leading to the amplification of adjacent cell damage. No previous study has addressed gap junctions and miRNAs in sepsis because the internal mechanism of sepsis-induced… read more here.
Keywords: sepsis; sirt1 foxo3a; mir 181b; cx43 ... See more keywords
LncRNA SNHG12 improves cerebral ischemic-reperfusion injury by activating SIRT1/FOXO3a pathway through inhibition of autophagy and oxidative stress.
Sign Up to like & getrecommendations! Published in 2020 at "Current neurovascular research"
DOI: 10.2174/1567202617666200727142019
Abstract: BACKGROUND Ischemia/reperfusion (I/R) injury involves complex biological processes and molecular mechanisms such as autophagy. Oxidative stress plays a critical role in the pathogenesis of I/R injury. LncRNAs are the regulatory factor of cerebral I/R injury.… read more here.
Keywords: sirt1 foxo3a; oxidative stress; autophagy oxidative; injury ... See more keywords
Cordyceps cicadae Ameliorates Renal Hypertensive Injury and Fibrosis Through the Regulation of SIRT1-Mediated Autophagy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.801094
Abstract: Hypertensive renal injury is a complication of hypertension. Cordyceps cicadae (C. cicadae) is a traditional Chinese medicine used to treat chronic kidney diseases especially renal fibrosis. Autophagy is described as a cell self-renewal process that… read more here.
Keywords: cicadae ameliorates; sirt1 foxo3a; expression; cordyceps cicadae ... See more keywords