NAD+ Precursors Reverse Experimental Diabetic Neuropathy in Mice
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DOI: 10.3390/ijms25021102
Abstract: Abnormal NAD+ signaling has been implicated in axonal degeneration in diabetic peripheral neuropathy (DPN). We hypothesized that supplementing NAD+ precursors could alleviate DPN symptoms through increasing the NAD+ levels and activating the sirtuin-1 (SIRT1) protein.… read more here.
Keywords: mice; sirt1 protein; nad precursors; reverse experimental ... See more keywords