Evaluation of the Neuroprotective Effect of Sirt3 in Experimental Stroke
Sign Up to like & getrecommendations! Published in 2017 at "Translational Stroke Research"
DOI: 10.1007/s12975-017-0603-x
Abstract: Sirtuins (Sirt) are a family of NAD+ dependent histone deacetylase (HDAC) proteins implicated in aging, cell cycle regulation, and metabolism. These proteins are involved in the epigenetic modification of neuromodulatory proteins after strokevia acetylation/deacetylation. The… read more here.
Keywords: neuroprotective effect; effect sirt3; sirt3 mice; evaluation neuroprotective ... See more keywords
36-OR: Energy Stress Restores Muscle Insulin Action in High-Fat (HF)-Fed SIRT3 KO Mice
Sign Up to like & getrecommendations! Published in 2019 at "Diabetes"
DOI: 10.2337/db19-36-or
Abstract: SIRT3 is a mitochondrial deacetylase that is necessary for insulin-stimulated muscle glucose uptake (MGU) in the setting of overnutrition, and its action is redox state-dependent (NAD/NADH). Energy stress induced by AICAR administration increases muscle insulin… read more here.
Keywords: sirt3 mice; mice; insulin; energy stress ... See more keywords