SIRT6 abrogation promotes adrenocortical carcinoma through activation of NF-κB signaling
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DOI: 10.1007/s11010-019-03525-8
Abstract: As an uncommon malignancy in the adrenal gland, adrenocortical carcinoma (ACC) is characterized by thorny diagnosis and poor clinical outcome, necessitating innovative treatment strategies. Sirtuin 6 (SIRT6), a tumor suppressor, modulates aerobic glycolysis of malignant… read more here.
Keywords: adrenocortical carcinoma; carcinoma; abrogation promotes; sirt6 knockdown ... See more keywords