Articles with "sirt6 activator" as a keyword



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MDL-800, the SIRT6 Activator, Suppresses Inflammation via the NF-κB Pathway and Promotes Angiogenesis to Accelerate Cutaneous Wound Healing in Mice

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Published in 2022 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2022/1619651

Abstract: Sirtuin 6 (SIRT6) is an NAD+-dependent deacetylase belonging to the sirtuin family. It has been shown to participate in wound healing and some inflammation-related disorders. However, the effect of MDL-800, a highly efficient and selective… read more here.

Keywords: inflammation; wound healing; mdl 800; sirt6 activator ... See more keywords
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The Identification of a SIRT6 Activator from Brown Algae Fucus distichus

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Published in 2017 at "Marine Drugs"

DOI: 10.3390/md15060190

Abstract: Brown seaweeds contain many bioactive compounds, including polyphenols, polysaccharides, fucosterol, and fucoxantin. These compounds have several biological activities, including anti-inflammatory, hepatoprotective, anti-tumor, anti-hypertensive, and anti-diabetic activity, although in most cases their mechanisms of action are… read more here.

Keywords: identification sirt6; brown algae; algae fucus; fucus ... See more keywords