Chrysophanol prevents IL-1β-Induced inflammation and ECM degradation in Osteoarthritis via the Sirt6/NF-κB and Nrf2/NF-κB axis.
Sign Up to like & getrecommendations! Published in 2022 at "Biochemical pharmacology"
DOI: 10.2139/ssrn.4217537
Abstract: Osteoarthritis (OA) is a common joint illness that negatively impacts people's lives. The main active ingredient of cassia seed or rhubarb is chrysophanol. It has various pharmacological effects including anticancer, anti-diabetes and blood lipid regulation.… read more here.
Keywords: nrf2 axis; osteoarthritis; sirt6 nrf2; chrysophanol ... See more keywords