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Sirtuin-mediated deacetylation of hnRNP A1 suppresses glycolysis and growth in hepatocellular carcinoma

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0 Published in 2019 at "Oncogene"

DOI: 10.1038/s41388-019-0764-z

Abstract: Tumor cells undergo a metabolic shift in order to adapt to the altered microenvironment, although the underlying mechanisms have not been fully explored. HnRNP A1 is involved in the alternative splicing of the pyruvate kinase… read more here.

Keywords: hepatocellular carcinoma; hnrnp; glycolysis; hcc cells ... See more keywords