Versatile role of sirtuins in metabolic disorders: From modulation of mitochondrial function to therapeutic interventions
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23047
Abstract: Sirtuins (SIRT1–7) are distinct histone deacetylases (HDACs) whose activity is determined by cellular metabolic status andnicotinamide adenine dinucleotide (NAD+) levels. HDACs of class III are the members of the SIRT's protein family. SIRTs are the… read more here.
Keywords: role; role sirtuins; heart; versatile role ... See more keywords
Sirtuins as Metabolic Regulators of Immune Cells Phenotype and Function
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DOI: 10.3390/genes12111698
Abstract: Beyond its role on the conversion of nutrients into energy and biomass, cellular metabolism is actively involved in the control of many physiological processes. Among these, it is becoming increasingly evident that specific metabolic pathways… read more here.
Keywords: metabolic regulators; sirtuins metabolic; regulators immune; function ... See more keywords