Study of the interaction of broad‐spectrum antimicrobial drug sitafloxacin with human serum albumin using spectroscopic methods, molecular docking, and molecular dynamics simulation
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DOI: 10.1016/j.jpba.2018.07.053
Abstract: HIGHLIGHTSThe interaction between sitafloxacin and human serum albumin has been firstly investigated.Quenching mechanism, binding constants, thermodynamic parameters, and binding modes were discussed and mutually confirmed.Molecular dynamics simulations were performed to further analyze the HSA‐sitafloxacin complex… read more here.
Keywords: sitafloxacin human; molecular dynamics; human serum; interaction ... See more keywords