Stability of extemporaneously prepared sitagliptin phosphate solution
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0262068
Abstract: Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that is used orally in conjunction with diet and exercise to control sugar levels in type 2 Diabetes Mellitus patients. This study aimed to extemporaneously prepare SiP solution… read more here.
Keywords: stability; extemporaneously prepared; sitagliptin phosphate; solution ... See more keywords
The development and validation of simultaneous quantitative analysis reversed-phase high-performance liquid chromatography for sitagliptin phosphate monohydrate and dapagliflozin propanediol monohydrate fixed-dose combination dual-layered tablet
Sign Up to like & getrecommendations! Published in 2023 at "Current Pharmaceutical Analysis"
DOI: 10.2174/1573412919666230417081123
Abstract: Sitagliptin phosphate monohydrate-dapagliflozin propanediol hydrate fixeddose combination (FDC) dual-layered tablet is used for type 2 diabetes treatment. Simultaneous quantitative analysis can shorten the analysis time of sitagliptin phosphate monohydrate-dapagliflozin propanediol monohydrate FDC dual-layered tablets and… read more here.
Keywords: monohydrate; dapagliflozin propanediol; monohydrate dapagliflozin; analysis ... See more keywords
Dipeptidyl Peptidase-4 Inhibitor Sitagliptin Phosphate Accelerates Cellular Cholesterol Efflux in THP-1 Cells
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DOI: 10.3390/biom13020228
Abstract: Cholesterol efflux is a major atheroprotective function of high-density lipoproteins (HDLs) which removes cholesterol from the foam cells of lipid-rich plaques in Type 2 diabetes. The dipeptidyl peptidase-4 (DPP-4) inhibitor sitagliptin phosphate increases plasma glucagon-like… read more here.
Keywords: glp; cholesterol; sitagliptin phosphate; cholesterol efflux ... See more keywords