Articles with "site identity" as a keyword



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A forward genetic screen in C. elegans identifies conserved residues of spliceosomal proteins PRP8 and SNRNP200/BRR2 with a role in maintaining 5′ splice site identity

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Published in 2022 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkac991

Abstract: Abstract The spliceosome undergoes extensive rearrangements as it assembles onto precursor messenger RNAs. In the earliest assembly step, U1snRNA identifies the 5′ splice site. However, U1snRNA leaves the spliceosome relatively early in assembly, and 5′… read more here.

Keywords: snrnp200 brr2; genetic screen; forward genetic; site identity ... See more keywords