Relationship of Catalysis and Active Site Loop Dynamics in the (βα)8-Barrel Enzyme Indole-3-glycerol Phosphate Synthase.
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DOI: 10.1021/acs.biochem.8b00167
Abstract: It is important to understand how the catalytic activity of enzymes is related to their conformational flexibility. We have studied this activity-flexibility correlation using the example of indole-3-glycerol phosphate synthase from Sulfolobus solfataricus (ssIGPS), which… read more here.
Keywords: site loop; active site; phosphate synthase; glycerol phosphate ... See more keywords