Uncovering a conserved vulnerability site in SARS-CoV-2 by a human antibody.
Sign Up to like & getrecommendations! Published in 2021 at "EMBO molecular medicine"
DOI: 10.15252/emmm.202114544
Abstract: An essential step for SARS-CoV-2 infection is the attachment to the host cell receptor by its Spike receptor-binding domain (RBD). Most of the existing RBD-targeting neutralizing antibodies block the receptor-binding motif (RBM), a mutable region… read more here.
Keywords: sars cov; vulnerability site; conserved vulnerability; site sars ... See more keywords
Identification and Inhibition of the Druggable Allosteric Site of SARS-CoV-2 NSP10/NSP16 Methyltransferase through Computational Approaches
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27165241
Abstract: Since its emergence in early 2019, the respiratory infectious virus, SARS-CoV-2, has ravaged the health of millions of people globally and has affected almost every sphere of life. Many efforts are being made to combat… read more here.
Keywords: allosteric site; site sars; nsp10 nsp16; methyltransferase ... See more keywords