Degradation of Non-coding RNAs Promotes Recycling of Termination Factors at Sites of Transcription.
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.107942
Abstract: A large share of the non-coding transcriptome in yeast is controlled by the Nrd1-Nab3-Sen1 (NNS) complex, which promotes transcription termination of non-coding RNA (ncRNA) genes, and by the nuclear exosome, which limits the steady-state levels… read more here.
Keywords: degradation; sites transcription; non coding; degradation non ... See more keywords
A novel SH2 recognition mechanism recruits Spt6 to the doubly phosphorylated RNA polymerase II linker at sites of transcription
Sign Up to like & getrecommendations! Published in 2017 at "eLife"
DOI: 10.7554/elife.28723
Abstract: We determined that the tandem SH2 domain of S. cerevisiae Spt6 binds the linker region of the RNA polymerase II subunit Rpb1 rather than the expected sites in its heptad repeat domain. The 4 nM… read more here.
Keywords: spt6; sites transcription; sh2; rna polymerase ... See more keywords