Articles with "sites trastuzumab" as a keyword



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Assessment of susceptible chemical modification sites of trastuzumab and endogenous human immunoglobulins at physiological conditions

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Published in 2018 at "Communications Biology"

DOI: 10.1038/s42003-018-0032-8

Abstract: The quality control testing of chemical degradations in the bio-pharmaceutical industry is currently under controversial debate. Here we have systematically applied in vitro and in vivo stress conditions to investigate the influence of protein degradation… read more here.

Keywords: chemical modification; degradation; modification sites; sites trastuzumab ... See more keywords