Articles with "situ cancer" as a keyword



Biomaterial-Based In Situ Cancer Vaccine.

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Published in 2023 at "Advanced materials"

DOI: 10.1002/adma.202210452

Abstract: Cancer immunotherapies have reshaped the paradigm for cancer treatment over the past decade. Among them, therapeutic cancer vaccines that aim to modulate antigen presenting cells (e.g., dendritic cells (DCs)) and subsequent T cell priming processes… read more here.

Keywords: cancer vaccine; based situ; cancer vaccines; situ cancer ... See more keywords

Long-Acting In Situ Cancer Vaccines by Oncolytic STING-Activating Microgels.

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Published in 2025 at "Small"

DOI: 10.1002/smll.202503561

Abstract: In situ cancer vaccines exploiting endogenous multiple antigens directly from tumors to elicit broad immune responses hold great potential in cancer treatment. However, the feeble antigen presentation and hostile immune microenvironments pose severe challenges to… read more here.

Keywords: cancer; situ cancer; activating microgels; cancer vaccines ... See more keywords

Cowpea Mosaic Virus and Natural Killer Cell Agonism for In Situ Cancer Vaccination.

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Published in 2022 at "Nano letters"

DOI: 10.1021/acs.nanolett.2c01328

Abstract: We have previously shown the plant virus Cowpea mosaic virus (CPMV) to be an efficacious in situ cancer vaccine, providing elimination of tumors and tumor-specific immune memory. Additionally, we have shown that CPMV recruits Natural… read more here.

Keywords: situ cancer; virus; cpmv; cowpea mosaic ... See more keywords

In Situ Cancer Vaccination and Immunovirotherapy Using Oncolytic HSV

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Published in 2021 at "Viruses"

DOI: 10.3390/v13091740

Abstract: Herpes simplex virus (HSV) can be genetically altered to acquire oncolytic properties so that oncolytic HSV (oHSV) preferentially replicates in and kills cancer cells, while sparing normal cells, and inducing anti-tumor immune responses. Over the… read more here.

Keywords: hsv; immunovirotherapy; oncolytic hsv; cancer ... See more keywords