Biomaterial-Based In Situ Cancer Vaccine.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced materials"
DOI: 10.1002/adma.202210452
Abstract: Cancer immunotherapies have reshaped the paradigm for cancer treatment over the past decade. Among them, therapeutic cancer vaccines that aim to modulate antigen presenting cells (e.g., dendritic cells (DCs)) and subsequent T cell priming processes… read more here.
Keywords: cancer vaccine; based situ; cancer vaccines; situ cancer ... See more keywords
Cowpea Mosaic Virus and Natural Killer Cell Agonism for In Situ Cancer Vaccination.
Sign Up to like & getrecommendations! Published in 2022 at "Nano letters"
DOI: 10.1021/acs.nanolett.2c01328
Abstract: We have previously shown the plant virus Cowpea mosaic virus (CPMV) to be an efficacious in situ cancer vaccine, providing elimination of tumors and tumor-specific immune memory. Additionally, we have shown that CPMV recruits Natural… read more here.
Keywords: situ cancer; virus; cpmv; cowpea mosaic ... See more keywords
In Situ Cancer Vaccination and Immunovirotherapy Using Oncolytic HSV
Sign Up to like & getrecommendations! Published in 2021 at "Viruses"
DOI: 10.3390/v13091740
Abstract: Herpes simplex virus (HSV) can be genetically altered to acquire oncolytic properties so that oncolytic HSV (oHSV) preferentially replicates in and kills cancer cells, while sparing normal cells, and inducing anti-tumor immune responses. Over the… read more here.
Keywords: hsv; immunovirotherapy; oncolytic hsv; cancer ... See more keywords