In Situ Forming Injectable Silk Fibroin Hydrogel Promotes Skin Regeneration in Full Thickness Burn Wounds
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.201801092
Abstract: Full-thickness skin wounds, associated with deep burns or chronic wounds pose a major clinical problem. Herein, the development of in situ forming hydrogel using a natural silk fibroin (SF) biomaterial for treating burn wounds is… read more here.
Keywords: burn; full thickness; hydrogel; situ forming ... See more keywords
In situ-forming and pH-responsive hydrogel based on chitosan for vaginal delivery of therapeutic agents
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Materials Science: Materials in Medicine"
DOI: 10.1007/s10856-018-6166-x
Abstract: AbstractOne of the important routes of drug administration for localized delivery of contraceptives and cervical cancer treatment agents is vaginal canal. Due to the low pH of vagina, a pH-responsive drug delivery system was developed.… read more here.
Keywords: hydrogel; linking density; delivery; situ forming ... See more keywords
In situ forming hydrogels based on polyethylene glycol itaconate for tissue engineering application
Sign Up to like & getrecommendations! Published in 2019 at "Bulletin of Materials Science"
DOI: 10.1007/s12034-019-1833-1
Abstract: Novel strategies have been proposed to enhance the quality of surgery by scheming noninvasive methods. For this reason, photo-curable in situ forming hydrogels have been well developed during advancements in the regenerative medicine. In this… read more here.
Keywords: polyethylene glycol; situ forming; situ; forming hydrogels ... See more keywords
Peppermint oil/doxycycline hyclate-loaded Eudragit RS in situ forming gel for periodontitis treatment
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DOI: 10.1007/s40005-017-0340-x
Abstract: Antibiotic-loaded in situ forming gels are particularly attractive for periodontitis treatment. They are in a sol form and gradually alter to a solid-like depot after administration into a periodontal pocket to deliver and maintain the… read more here.
Keywords: forming gel; situ forming; peppermint oil; periodontitis treatment ... See more keywords
Ultrafast in situ forming poly(ethylene glycol)‐poly(amido amine) hydrogels with tunable drug release properties via controllable degradation rates
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Pharmaceutics and Biopharmaceutics"
DOI: 10.1016/j.ejpb.2019.04.006
Abstract: ABSTRACT Fast in situ forming, chemically crosslinked hydrogels were prepared by the amidation reaction between N‐succinimidyl ester end groups of multi‐armed poly(ethylene glycol) (PEG) and amino surface groups of poly(amido amine) (PAMAM) dendrimer generation 2.0.… read more here.
Keywords: degradation; situ forming; poly ethylene; peg pamam ... See more keywords
In-situ forming implants for the treatment of periodontal diseases: Simultaneous controlled release of an antiseptic and an anti-inflammatory drug.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2019.118833
Abstract: Different types of in-situ forming implants based on poly(lactic-co-glycolic acid) (PLGA) for the controlled dual release of an antiseptic drug (chlorhexidine) and an anti-inflammatory drug (ibuprofen) were prepared and thoroughly characterized in vitro. N-methyl-pyrrolidone (NMP)… read more here.
Keywords: anti inflammatory; forming implants; release antiseptic; situ forming ... See more keywords
Mucoadhesive In Situ Forming Gel for Oral Mucositis Pain Control.
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DOI: 10.1016/j.ijpharm.2020.119238
Abstract: The current first line therapy for oral mucositis pain control is unsatisfactory as it results in only a short duration of modest pain relief. Developing mucoadhesive in situ forming formulations to prolong pain relief is… read more here.
Keywords: situ forming; pain control; pain; oral mucositis ... See more keywords
An in vitro gel-based system for characterizing and predicting the long-term performance of PLGA in situ forming implants.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2021.121183
Abstract: In situ forming implants are exposed to an extracellular matrix resembling a gel rather than aqueous solution upon subcutaneous administration. The aim of study was to develop a gel-based release testing system for characterizing the… read more here.
Keywords: based system; forming implants; system; situ forming ... See more keywords
Development of injectable tenoxicam in situ forming microparticles based on sesame oil and poly-DL-lactide: Characterization, efficacy and acute toxicity
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2019.04.001
Abstract: Abstract The aim of this research is to develop sustained release Tenoxicam (TNX) in situ forming microparticles to substitute the conventional oral dosage forms for the treatment of rheumatoid arthritis (RA). This new formulation is… read more here.
Keywords: release; efficacy; acute toxicity; situ forming ... See more keywords
Optimization of injectable PLGA in-situ forming implants of anti-psychotic risperidone via Box-Behnken Design
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2020.101803
Abstract: Abstract The current study aims to develop in-situ forming implants (ISFI) of anti-psychotic risperidone to customize schizophrenia therapy. Non-adherence to treatment is the most prevalent unsuccessful clinical outcome in schizophrenic patients. Poly(lactic-co-glycolic acid) (PLGA) was… read more here.
Keywords: forming implants; situ forming; psychotic risperidone; anti psychotic ... See more keywords
Green synthesis of in situ forming alginate-urethane hydrogel through Schiff base reaction
Sign Up to like & getrecommendations! Published in 2019 at "Materials Letters"
DOI: 10.1016/j.matlet.2019.07.052
Abstract: Abstract Despite recent advances in preparing hydrogels, their application is mainly limited due to the poor mechanical properties or the high risk of inflammatory response. Therefore, in this study a fully defined in situ hydrogelation… read more here.
Keywords: forming alginate; synthesis situ; alginate urethane; situ forming ... See more keywords