Articles with "situ gelling" as a keyword



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In Situ Gelling Hydrogel with Anti-Bacterial Activity and Bone Healing Property for Treatment of Osteomyelitis

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Published in 2019 at "Tissue Engineering and Regenerative Medicine"

DOI: 10.1007/s13770-019-00206-x

Abstract: Despite the development of progressive surgical techniques and antibiotics, osteomyelitis is a big challenge for orthopedic surgeons. The main aim of this study is to fabricate an in situ gelling hydrogel that permits sustained release… read more here.

Keywords: vancomycin bmp; hydrogel; situ gelling; anti bacterial ... See more keywords
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Cyanine derivative as a suitable marker for thermosensitive in situ gelling delivery systems: In vitro and in vivo validation of a sustained buccal drug delivery.

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Published in 2017 at "International journal of pharmaceutics"

DOI: 10.1016/j.ijpharm.2017.09.073

Abstract: Buccal administration route is a promising way for a large number of drugs exhibiting a low oral bioavailability. The present work describes the formulation and evaluation of a mucoadhesive and thermosensitive in situ gelling delivery… read more here.

Keywords: thermosensitive situ; situ gelling; delivery; gelling delivery ... See more keywords
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Oral raft forming in situ gelling system for site specific delivery of calcium

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Published in 2020 at "Journal of Drug Delivery Science and Technology"

DOI: 10.1016/j.jddst.2020.102113

Abstract: Abstract In situ gelling Raft forming system (GRFS), a novel sol-gel system of calcium carbonate (CC) was developed with the aim to prolong the gastric residence time and thereby the bioavailability. A simple lattice mixture… read more here.

Keywords: calcium; raft forming; system; situ gelling ... See more keywords
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In situ Gelling Amphotericin B Nanofibers: A New Option for the Treatment of Keratomycosis

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Published in 2020 at "Frontiers in Bioengineering and Biotechnology"

DOI: 10.3389/fbioe.2020.600384

Abstract: The purpose of our research was the development of Amphotericin B-loaded in situ gelling nanofibers for the treatment of keratomycosis. Different formulation strategies were applied to increase the drug load of the sparingly water-soluble Amphotericin… read more here.

Keywords: polyelectrolyte complex; situ gelling; treatment keratomycosis; amphotericin ... See more keywords
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Optimization of the Micellar-Based In Situ Gelling Systems Posaconazole with Quality by Design (QbD) Approach and Characterization by In Vitro Studies

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Published in 2022 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics14030526

Abstract: Background: Fungal ocular infections can cause serious consequences, despite their low incidence. It has been reported that Posaconazole (PSC) is used in the treatment of fungal infections in different ocular tissues by diluting the oral… read more here.

Keywords: optimization micellar; situ gelling; qbd approach; based situ ... See more keywords