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Published in 2019 at "Tissue Engineering and Regenerative Medicine"
DOI: 10.1007/s13770-019-00206-x
Abstract: Despite the development of progressive surgical techniques and antibiotics, osteomyelitis is a big challenge for orthopedic surgeons. The main aim of this study is to fabricate an in situ gelling hydrogel that permits sustained release…
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Keywords:
vancomycin bmp;
hydrogel;
situ gelling;
anti bacterial ... See more keywords
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Published in 2017 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2017.09.073
Abstract: Buccal administration route is a promising way for a large number of drugs exhibiting a low oral bioavailability. The present work describes the formulation and evaluation of a mucoadhesive and thermosensitive in situ gelling delivery…
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Keywords:
thermosensitive situ;
situ gelling;
delivery;
gelling delivery ... See more keywords
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Published in 2020 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2020.102113
Abstract: Abstract In situ gelling Raft forming system (GRFS), a novel sol-gel system of calcium carbonate (CC) was developed with the aim to prolong the gastric residence time and thereby the bioavailability. A simple lattice mixture…
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Keywords:
calcium;
raft forming;
system;
situ gelling ... See more keywords
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Published in 2020 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2020.600384
Abstract: The purpose of our research was the development of Amphotericin B-loaded in situ gelling nanofibers for the treatment of keratomycosis. Different formulation strategies were applied to increase the drug load of the sparingly water-soluble Amphotericin…
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Keywords:
polyelectrolyte complex;
situ gelling;
treatment keratomycosis;
amphotericin ... See more keywords
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Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14030526
Abstract: Background: Fungal ocular infections can cause serious consequences, despite their low incidence. It has been reported that Posaconazole (PSC) is used in the treatment of fungal infections in different ocular tissues by diluting the oral…
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Keywords:
optimization micellar;
situ gelling;
qbd approach;
based situ ... See more keywords