In situ glucosylceramide synthesis and its pharmacological inhibition analysed in cells by 13C5‐sphingosine precursor feeding and mass spectrometry
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DOI: 10.1002/1873-3468.14448
Abstract: Glycosphingolipids (GSLs) fulfil diverse functions in cells. Abnormalities in their metabolism are associated with specific pathologies and, consequently, the pharmacological modulation of GSLs is considered a therapeutic avenue. The accurate measurement of in situ metabolism of… read more here.
Keywords: mass spectrometry; precursor; situ glucosylceramide; synthesis ... See more keywords