In situ heart valve tissue engineering using a bioresorbable elastomeric implant - From material design to 12 months follow-up in sheep.
Sign Up to like & getrecommendations! Published in 2017 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2017.02.007
Abstract: The creation of a living heart valve is a much-wanted alternative for current valve prostheses that suffer from limited durability and thromboembolic complications. Current strategies to create such valves, however, require the use of cells… read more here.
Keywords: engineering; heart; situ heart; valve tissue ... See more keywords
Reduced Flow during Ex-Situ Heart Perfusion Provides Superior Function Preservation and Less Edema Formation
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Heart and Lung Transplantation"
DOI: 10.1016/j.healun.2021.01.1770
Abstract: Purpose Ex-situ heart perfusion (ESHP) allows continuous functional and metabolic resuscitation of donor hearts before transplantation. Evidence indicates that hearts that are perfused under physiologic conditions lose the normal vasomotor tone and fail in a… read more here.
Keywords: perfusion; heart; flow situ; heart perfusion ... See more keywords
The Position of the Heart During Normothermic Ex Situ Heart Perfusion is an Important Factor in Preservation and Recovery of Myocardial Function
Sign Up to like & getrecommendations! Published in 2021 at "ASAIO Journal"
DOI: 10.1097/mat.0000000000001386
Abstract: Supplemental Digital Content is available in the text. Ex situ heart perfusion (ESHP) is being investigated as a method for the continuous preservation of the myocardium in a semiphysiologic state for subsequent transplantation. Most methods… read more here.
Keywords: preservation; perfusion; heart; position ... See more keywords
The Impact of Ex Situ Heart Perfusion in Pediatric Transplantation: An Analysis of the United Network for Organ Sharing Registry.
Sign Up to like & getrecommendations! Published in 2022 at "ASAIO journal"
DOI: 10.1097/mat.0000000000001738
Abstract: Ex situ heart perfusion (ESHP) has increased the pool of donors in adults. However, this is not true in pediatrics due to lack of devices. Therefore, we sought to understand organ refusal in pediatrics and… read more here.
Keywords: distance; heart; network organ; heart perfusion ... See more keywords
Barriers and misconceptions of ex situ heart perfusion in pediatric donation
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DOI: 10.1111/petr.14387
Abstract: Despite efforts, pediatric HTx candidates continue to have high waitlist mortality due to limited donor availability. However, there is a significant number of offered hearts not used due to concerns of viability. ESHP is a… read more here.
Keywords: barriers misconceptions; perfusion; heart; heart perfusion ... See more keywords
Dynamic Metabolic Changes During Prolonged Ex Situ Heart Perfusion Are Associated With Myocardial Functional Decline
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.859506
Abstract: Ex situ heart perfusion (ESHP) was developed to preserve and evaluate donated hearts in a perfused beating state. However, myocardial function declines during ESHP, which limits the duration of perfusion and the potential to expand… read more here.
Keywords: spme; perfusion; heart perfusion; heart ... See more keywords