510 Transitioning to an In-House In-Situ Hybridisation Assay Accelerates Indeterminate HER-2 Lesion Results
Sign Up to like & getrecommendations! Published in 2021 at "British Journal of Surgery"
DOI: 10.1093/bjs/znab259.209
Abstract: NICE guidelines 1.6.5 recommend that: ‘HER2 status [should be] available and recorded at the pre-operative multidisciplinary team (MDT) meeting when systemic treatment is discussed,’ to aid decision-making regarding neoadjuvant therapy. However, indeterminate HER2 lesions require… read more here.
Keywords: situ hybridisation; her2 status; time; decision making ... See more keywords
Genetic characterisation of childhood B-other-acute lymphoblastic leukaemia in UK patients by fluorescence in situ hybridisation and Multiplex Ligation-dependent Probe Amplification.
Sign Up to like & getrecommendations! Published in 2021 at "British journal of haematology"
DOI: 10.1111/bjh.17869
Abstract: While next-generation sequencing technologies provide excellent strategies to screen for newly defined genetic abnormalities of prognostic or therapeutic significance in patients with B-other-acute lymphoblastic leukaemia (ALL), they are not widely available. We used a dual… read more here.
Keywords: situ hybridisation; fluorescence situ; lymphoblastic leukaemia; multiplex ligation ... See more keywords
Use of fluorescent in‐situ hybridisation in salivary gland cytology: A powerful diagnostic tool
Sign Up to like & getrecommendations! Published in 2017 at "Cytopathology"
DOI: 10.1111/cyt.12427
Abstract: Salivary gland cytology is challenging because it includes a diversity of lesions and a wide spectra of tumours. Recently, it has been reported that many types of salivary gland tumours have specific molecular diagnostic signatures… read more here.
Keywords: fluorescent situ; situ hybridisation; salivary gland; gland cytology ... See more keywords
A genomic and clinicopathological study of non‐small‐cell lung cancers with discordant ROS1 gene status by fluorescence in‐situ hybridisation and immunohistochemical analysis
Sign Up to like & getrecommendations! Published in 2018 at "Histopathology"
DOI: 10.1111/his.13492
Abstract: ROS1 immunohistochemistry (IHC) using D4D6 antibody is a useful tool for screening patients with non‐small‐cell lung cancer (NSCLC) who may be suitable for targeted therapy. Many studies and our data have identified cases that express… read more here.
Keywords: situ hybridisation; fluorescence situ; cell lung; non small ... See more keywords
Single-transcript multiplex in situ hybridisation reveals unique patterns of dystrophin isoform expression in the developing mammalian embryo
Sign Up to like & getrecommendations! Published in 2020 at "Wellcome Open Research"
DOI: 10.12688/wellcomeopenres.15762.2
Abstract: Background: The dystrophin gene has multiple isoforms: full-length dystrophin (dp427) is principally known for its expression in skeletal and cardiac muscle, but is also expressed in the brain, and several internal promoters give rise to… read more here.
Keywords: situ hybridisation; single transcript; isoform expression; expression ... See more keywords
Improvement of diagnosis in children with Burkitt lymphoma in Kenya: feasibility study for the implementation of fluorescence in situ hybridisation testing for MYC and the MYC/IGH translocation
Sign Up to like & getrecommendations! Published in 2023 at "ecancermedicalscience"
DOI: 10.3332/ecancer.2023.1505
Abstract: Background Indiana University (IU) initiated fluorescence in situ hybridisation (FISH) methodology for Burkitt Lymphoma (BL) to advance the accuracy and speed of diagnosis in the AMPATH Reference Laboratory at Moi Teaching and Referral Hospital (MTRH)… read more here.
Keywords: situ hybridisation; diagnosis; myc myc; fluorescence situ ... See more keywords
Advances in Viral Aquatic Animal Disease Knowledge: The Molecular Methods’ Contribution
Sign Up to like & getrecommendations! Published in 2023 at "Biology"
DOI: 10.3390/biology12030466
Abstract: Simple Summary Viruses are pervasive components of aquatic ecosystems, and most of them are harmless to humans and animals; however, several aquatic viruses can infect animals, leading to diseases, especially when fish are confined, such… read more here.
Keywords: situ hybridisation; aquatic animal; disease; molecular methods ... See more keywords
Improvement of RNA In Situ Hybridisation for Grapevine Fruits and Ovules
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24010800
Abstract: The European grapevine (Vitis vinifera L.) is one of the world’s most widely cultivated and economically important fruit crops. Seedless fruits are particularly desired for table grapes, with seedlessness resulting from stenospermocarpy being an important… read more here.
Keywords: improvement; situ hybridisation; hybridisation; grapevine ... See more keywords