In Situ Injectable Sequentially Responsive Hydrogel Based on Triblock Copolymers for Breast Cancer Theranostic Amplification.
Sign Up to like & getrecommendations! Published in 2025 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.5c00320
Abstract: Celastrol (Cel), a natural small molecule, effectively inhibits breast cancer but has poor solubility and systemic toxicity. Herein, an in situ injectable sequentially responsive celastrol hydrogel (FCPC) based on the temperature-sensitive poloxamer F127 and tumor-acidity-cleavable… read more here.
Keywords: situ injectable; sequentially responsive; breast cancer; responsive hydrogel ... See more keywords
Dual Aptamer-Functionalized in Situ Injectable Fibrin Hydrogel for Promotion of Angiogenesis via Codelivery of Vascular Endothelial Growth Factor and Platelet-Derived Growth Factor-BB.
Sign Up to like & getrecommendations! Published in 2019 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.9b02462
Abstract: In situ injectable hydrogels hold great potential for in vivo applications such as drug delivery and regenerative medicine. However, it is challenging to ensure stable sequestration and sustained release of loaded biomolecules in these hydrogels.… read more here.
Keywords: growth factor; growth; situ injectable; aptamer functionalized ... See more keywords
SILK FIBROIN-BASED ANASTROZOLE NANOPARTICLE LOADED IN SITU INJECTABLE: DEVELOPMENT AND CHARACTERIZATION
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Applied Pharmaceutics"
DOI: 10.22159/ijap.2023v15i3.47593
Abstract: Objective: The study aims to find a suitable method of developing silk fibroin-based anastrozole nanoparticles and formulate in situ injectables by loading the optimized nanoparticle formulation for the sustained release treatment of breast cancer. Methods:… read more here.
Keywords: fibroin based; spectroscopy; silk fibroin; based anastrozole ... See more keywords