A Bioactive compound Shatavarin IV-mediated longevity as revealed by dietary restriction-induced autophagy in Caenorhabditis elegans
Sign Up to like & getrecommendations! Published in 2020 at "Biogerontology"
DOI: 10.1007/s10522-020-09897-5
Abstract: Plant-based dietary supplements that delay aging are of significant interest now a days because these naturally occurring bioactive molecules effectively provide pharmaceuticals/neutraceuticals to deal with diseases related to the advanced life expectancy. In this paper,… read more here.
Keywords: longevity; effect; siv; dietary restriction ... See more keywords
Persistence of SIV in the brain of SIV-infected Chinese rhesus macaques with or without antiretroviral therapy
Sign Up to like & getrecommendations! Published in 2017 at "Journal of NeuroVirology"
DOI: 10.1007/s13365-017-0594-0
Abstract: Persistence of HIV-1 reservoirs in the central nervous system (CNS) is an obstacle to cure strategies. However, little is known about residual viral distribution, viral replication levels, and genetic diversity in different brain regions of… read more here.
Keywords: antiretroviral therapy; chinese rhesus; siv; brain ... See more keywords
Development of novel replication-defective lymphocytic choriomeningitis virus vectors expressing SIV antigens.
Sign Up to like & getrecommendations! Published in 2017 at "Vaccine"
DOI: 10.1016/j.vaccine.2016.11.063
Abstract: An important focus in vaccine research is the design of vaccine vectors with low seroprevalence and high immunogenicity. Replication-incompetent lymphocytic choriomeningitis virus (rLCMV) vectors do not elicit vector-neutralizing antibody responses, and homologous prime-boost regimens with… read more here.
Keywords: choriomeningitis virus; siv; vectors expressing; vaccine ... See more keywords
Healthcare worker's attitude to seasonal influenza vaccination in the South Tyrolean province of Italy: barriers and facilitators.
Sign Up to like & getrecommendations! Published in 2018 at "Vaccine"
DOI: 10.1016/j.vaccine.2017.12.007
Abstract: BACKGROUND Seasonal influenza vaccination (SIV) is an effective and safe way to prevent influenza. Public health institutions around the world consequently recommend SIV to certain groups at risk, including healthcare worker's (HCWs). Even if SIV… read more here.
Keywords: healthcare worker; south tyrolean; seasonal influenza; siv ... See more keywords
Early Treatment of SIV+ macaques with an α4β7 mAb alters virus distribution and preserves CD4+ T cells in later stages of infection
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DOI: 10.1038/mi.2017.112
Abstract: Integrin α4β7 mediates the trafficking of leukocytes, including CD4+ T cells, to lymphoid tissues in the gut. Virus mediated damage to the gut is implicated in HIV and SIV mediated chronic immune activation and leads… read more here.
Keywords: cd4 cells; stages infection; treatment; siv ... See more keywords
PPARα-targeted mitochondrial bioenergetics mediate repair of intestinal barriers at the host–microbe intersection during SIV infection
Sign Up to like & getrecommendations! Published in 2019 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1908977116
Abstract: Significance Our study has identified that impaired peroxisome proliferator-activated receptor-α (PPARα) signaling and associated mitochondrial dysfunction is an important underlying mechanism for prolonged leaky gut barriers in HIV and Simian immunodeficiency virus (SIV) infections despite… read more here.
Keywords: ppar; recovery; intersection; epithelium ... See more keywords
PD-1 blockade following ART interruption enhances control of pathogenic SIV in rhesus macaques
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2202148119
Abstract: Significance Anti-viral CD8 T cells express high levels of the co-inhibitory receptor programmed death-1 (PD-1) during chronic HIV and Simian immunodeficiency virus (SIV) infections and in vivo PD-1 blockade during chronic SIV infection restores CD8… read more here.
Keywords: control; blockade following; blockade; following art ... See more keywords
Contribution of Innate Lymphoid Cells in Supplementing Cytokines Produced by CD4+ T-cells During Acute and Chronic SIV Infection of the Colon.
Sign Up to like & getrecommendations! Published in 2022 at "AIDS research and human retroviruses"
DOI: 10.1089/aid.2022.0007
Abstract: HIV/SIV infection leads to a loss of CD4+ T-helper (Th) cells in number and function that begins during the acute phase and persists through the chronic phase of infection. In particular, there is a drastic… read more here.
Keywords: siv; innate lymphoid; lymphoid cells; siv infection ... See more keywords
Differential regulation of tachykinin and opioid system gene expression in brain and immune cells of chronic binge alcohol-treated, simian immunodeficiency virus (SIV)-infected macaques.
Sign Up to like & getrecommendations! Published in 2023 at "AIDS research and human retroviruses"
DOI: 10.1089/aid.2022.0122
Abstract: People living with HIV (PLWH) have a high likelihood of at-risk alcohol use and are at increased risk for neurocognitive decline. The underlying mechanisms involved in HIV-associated neurocognitive disorder (HAND) are not completely understood. Previously,… read more here.
Keywords: expression; gene expression; alcohol; cba ... See more keywords
Upregulation of Superoxide Dismutase 2 by Astrocytes in the SIV/Macaque Model of HIV-Associated Neurologic Disease.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of neuropathology and experimental neurology"
DOI: 10.1093/jnen/nlaa084
Abstract: HIV-associated neurocognitive disorders (HAND) remain prevalent despite implementation of antiretroviral therapy (ART). Development of HAND is linked to mitochondrial dysfunction and oxidative stress in the brain; therefore, upregulation of antioxidant defenses is critical to curtail… read more here.
Keywords: hiv; macaque model; siv; siv infected ... See more keywords
Swine Influenza Viruses and PandemicH1N1-2009 Infection in Pigs, Myanmar.
Sign Up to like & getrecommendations! Published in 2020 at "Transboundary and emerging diseases"
DOI: 10.1111/tbed.13616
Abstract: Swine influenza virus (SIV) causes respiratory diseases in pigs and has impacts on both animal and human health. In this study, we conducted swine influenza surveillance in pig farms in the Yangon and Bago regions,… read more here.
Keywords: swine influenza; sivs; myanmar; pdmh1n1 2009 ... See more keywords