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   Articles with "siv" as a keyword



A Bioactive compound Shatavarin IV-mediated longevity as revealed by dietary restriction-induced autophagy in Caenorhabditis elegans

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recommendations! Published in 2020 at "Biogerontology"

DOI: 10.1007/s10522-020-09897-5

Abstract: Plant-based dietary supplements that delay aging are of significant interest now a days because these naturally occurring bioactive molecules effectively provide pharmaceuticals/neutraceuticals to deal with diseases related to the advanced life expectancy. In this paper,… read more here.

Keywords: longevity; effect; siv; dietary restriction ... See more keywords

Persistence of SIV in the brain of SIV-infected Chinese rhesus macaques with or without antiretroviral therapy

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recommendations! Published in 2017 at "Journal of NeuroVirology"

DOI: 10.1007/s13365-017-0594-0

Abstract: Persistence of HIV-1 reservoirs in the central nervous system (CNS) is an obstacle to cure strategies. However, little is known about residual viral distribution, viral replication levels, and genetic diversity in different brain regions of… read more here.

Keywords: antiretroviral therapy; chinese rhesus; siv; brain ... See more keywords

Development of novel replication-defective lymphocytic choriomeningitis virus vectors expressing SIV antigens.

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recommendations! Published in 2017 at "Vaccine"

DOI: 10.1016/j.vaccine.2016.11.063

Abstract: An important focus in vaccine research is the design of vaccine vectors with low seroprevalence and high immunogenicity. Replication-incompetent lymphocytic choriomeningitis virus (rLCMV) vectors do not elicit vector-neutralizing antibody responses, and homologous prime-boost regimens with… read more here.

Keywords: choriomeningitis virus; siv; vectors expressing; vaccine ... See more keywords

Healthcare worker's attitude to seasonal influenza vaccination in the South Tyrolean province of Italy: barriers and facilitators.

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recommendations! Published in 2018 at "Vaccine"

DOI: 10.1016/j.vaccine.2017.12.007

Abstract: BACKGROUND Seasonal influenza vaccination (SIV) is an effective and safe way to prevent influenza. Public health institutions around the world consequently recommend SIV to certain groups at risk, including healthcare worker's (HCWs). Even if SIV… read more here.

Keywords: healthcare worker; south tyrolean; seasonal influenza; siv ... See more keywords

High-Yield Production of SiV-Doped Nanodiamonds for Spectroscopy and Sensing Applications

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recommendations! Published in 2024 at "ACS Applied Nano Materials"

DOI: 10.1021/acsanm.4c04676

Abstract: Nanodiamonds (NDs) containing optically active centers have gained significant relevance as the material of choice for biological, optoelectronic, and quantum applications. However, current production methods lag behind their real needs. This study introduces two CVD-based… read more here.

Keywords: spectroscopy; siv; high yield; yield production ... See more keywords

Early Treatment of SIV+ macaques with an α4β7 mAb alters virus distribution and preserves CD4+ T cells in later stages of infection

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recommendations! Published in 2017 at "Mucosal immunology"

DOI: 10.1038/mi.2017.112

Abstract: Integrin α4β7 mediates the trafficking of leukocytes, including CD4+ T cells, to lymphoid tissues in the gut. Virus mediated damage to the gut is implicated in HIV and SIV mediated chronic immune activation and leads… read more here.

Keywords: cd4 cells; stages infection; treatment; siv ... See more keywords

PPARα-targeted mitochondrial bioenergetics mediate repair of intestinal barriers at the host–microbe intersection during SIV infection

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recommendations! Published in 2019 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.1908977116

Abstract: Significance Our study has identified that impaired peroxisome proliferator-activated receptor-α (PPARα) signaling and associated mitochondrial dysfunction is an important underlying mechanism for prolonged leaky gut barriers in HIV and Simian immunodeficiency virus (SIV) infections despite… read more here.

Keywords: ppar; recovery; intersection; epithelium ... See more keywords

PD-1 blockade following ART interruption enhances control of pathogenic SIV in rhesus macaques

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recommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2202148119

Abstract: Significance Anti-viral CD8 T cells express high levels of the co-inhibitory receptor programmed death-1 (PD-1) during chronic HIV and Simian immunodeficiency virus (SIV) infections and in vivo PD-1 blockade during chronic SIV infection restores CD8… read more here.

Keywords: control; blockade following; blockade; following art ... See more keywords
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Contribution of Innate Lymphoid Cells in Supplementing Cytokines Produced by CD4+ T-cells During Acute and Chronic SIV Infection of the Colon.

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recommendations! Published in 2022 at "AIDS research and human retroviruses"

DOI: 10.1089/aid.2022.0007

Abstract: HIV/SIV infection leads to a loss of CD4+ T-helper (Th) cells in number and function that begins during the acute phase and persists through the chronic phase of infection. In particular, there is a drastic… read more here.

Keywords: siv; innate lymphoid; lymphoid cells; siv infection ... See more keywords

Differential regulation of tachykinin and opioid system gene expression in brain and immune cells of chronic binge alcohol-treated, simian immunodeficiency virus (SIV)-infected macaques.

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recommendations! Published in 2023 at "AIDS research and human retroviruses"

DOI: 10.1089/aid.2022.0122

Abstract: People living with HIV (PLWH) have a high likelihood of at-risk alcohol use and are at increased risk for neurocognitive decline. The underlying mechanisms involved in HIV-associated neurocognitive disorder (HAND) are not completely understood. Previously,… read more here.

Keywords: expression; gene expression; alcohol; cba ... See more keywords

CSF1R inhibition depletes brain macrophages and reduces brain virus burden in SIV-infected macaques

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recommendations! Published in 2024 at "Brain"

DOI: 10.1093/brain/awae153

Abstract: Abstract Perivascular macrophages (PVMs) and, to a lesser degree, microglia are targets and reservoirs of HIV and simian immunodeficiency virus (SIV) in the brain. Previously, we demonstrated that colony-stimulating factor 1 receptor (CSF1R) in PVMs… read more here.

Keywords: csf1r inhibition; brain; siv; virus ... See more keywords