A cellular trafficking signal in the SIV envelope protein cytoplasmic domain is strongly selected for in pathogenic infection
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DOI: 10.1371/journal.ppat.1010507
Abstract: The HIV/SIV envelope glycoprotein (Env) cytoplasmic domain contains a highly conserved Tyr-based trafficking signal that mediates both clathrin-dependent endocytosis and polarized sorting. Despite extensive analysis, the role of these functions in viral infection and pathogenesis… read more here.
Keywords: infection; siv envelope; trafficking signal; cytoplasmic domain ... See more keywords