Contribution of Innate Lymphoid Cells in Supplementing Cytokines Produced by CD4+ T-cells During Acute and Chronic SIV Infection of the Colon.
Sign Up to like & getrecommendations! Published in 2022 at "AIDS research and human retroviruses"
DOI: 10.1089/aid.2022.0007
Abstract: HIV/SIV infection leads to a loss of CD4+ T-helper (Th) cells in number and function that begins during the acute phase and persists through the chronic phase of infection. In particular, there is a drastic… read more here.
Keywords: siv; innate lymphoid; lymphoid cells; siv infection ... See more keywords
IFNα-blockade during ART-treated SIV infection lowers tissue vDNA, rescues immune function, and improves overall health.
Sign Up to like & getrecommendations! Published in 2022 at "JCI insight"
DOI: 10.1172/jci.insight.153046
Abstract: Type I interferons (TI-IFNs) drive immune effector functions during acute viral infections and regulate cell cycling and systemic metabolism. That said, chronic TI-IFN signaling in the context of antiretroviral therapy (ART)-treated HIV infection also facilitates… read more here.
Keywords: ifn; ifn blockade; art treated; siv infection ... See more keywords
Expansion of Immature Neutrophils During SIV Infection Is Associated With Their Capacity to Modulate T-Cell Function
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.781356
Abstract: In spite of the efficacy of combinational antiretroviral treatment (cART), HIV-1 persists in the host and infection is associated with chronic inflammation, leading to an increased risk of comorbidities, such as cardiovascular diseases, neurocognitive disorders,… read more here.
Keywords: cell; infection; infection associated; immature neutrophils ... See more keywords