miR‐802 inhibits the proliferation, invasion, and epithelial‐mesenchymal transition of glioblastoma multiforme cells by directly targeting SIX4
Sign Up to like & getrecommendations! Published in 2019 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3451
Abstract: It is well known that the sine oculis homeobox 4 (SIX4) expression is very relevant to the progression of multiple cancers. Moreover, we found that miR‐802 could directly target the SIX4. However, the precise mechanism… read more here.
Keywords: gbm; mir 802; proliferation invasion; six4 ... See more keywords
SIX4 upregulates IDH1 and metabolic reprogramming to promote osteosarcoma progression
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17650
Abstract: Metabolism reprogramming plays an important role in tumorigenesis and osteosarcoma metastasis. Sine oculis homeobox 4 (SIX4) is reported to be a key transcription factor that is involved in glycolysis reprogramming of cancer cells. However, the… read more here.
Keywords: osteosarcoma patients; six4; six4 upregulates; osteosarcoma progression ... See more keywords
IGF2BP3-stabilized SIX4 promotes the proliferation, migration, invasion and tube formation of ovarian cancer cells
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DOI: 10.3892/mmr.2022.12748
Abstract: The mortality rate of ovarian cancer (OC) is the highest among the different types of female reproductive system cancers. SIX homeobox 4 (SIX4), a member of the homeobox family, subfamily SIX, fulfills an important role… read more here.
Keywords: igf2bp3; migration; invasion; formation ... See more keywords
Comprehensive analysis of the potential role and prognostic value of sine oculis homeobox homolog family in colorectal cancer
Sign Up to like & getrecommendations! Published in 2022 at "World Journal of Gastrointestinal Oncology"
DOI: 10.4251/wjgo.v14.i11.2138
Abstract: BACKGROUND Several genes, important for development, are reduced or silenced in adulthood, and their abnormal expression has been related to the occurrence and development of malignant tumors. Human sine oculis homeobox homolog (SIX) proteins belong… read more here.
Keywords: sine oculis; family; expression; six4 ... See more keywords