Selective Inhibitors of Medium-Size S1' Pocket Matrix Metalloproteinases: A Stepping Stone of Future Drug Discovery.
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DOI: 10.1021/acs.jmedchem.1c01855
Abstract: Among various matrix metalloproteinases (MMPs), MMPs having medium-size S1' pockets are established as promising biomolecular targets for executing crucial roles in cancer, cardiovascular diseases, and neurodegenerative diseases. However, no such MMP inhibitors (MMPIs) are available… read more here.
Keywords: matrix metalloproteinases; size pocket; size; medium size ... See more keywords