Mobilizing Endogenous Progenitor Cells Using pSDF1α‐Activated Scaffolds Accelerates Angiogenesis and Bone Repair in Critical‐Sized Bone Defects
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202401031
Abstract: Mobilizing endogenous progenitor cells to repair damaged tissue in situ has the potential to revolutionize the field of regenerative medicine, while the early establishment of a vascular network will ensure survival of newly generated tissue.… read more here.
Keywords: endogenous progenitor; sized bone; bone; mobilizing endogenous ... See more keywords
Bone morphogenetic protein 2-induced cellular chemotaxis drives tissue patterning during critical-sized bone defect healing: an in silico study
Sign Up to like & getrecommendations! Published in 2021 at "Biomechanics and Modeling in Mechanobiology"
DOI: 10.1007/s10237-021-01466-0
Abstract: Critical-sized bone defects are critical healing conditions that, if left untreated, often lead to non-unions. To reduce the risk, critical-sized bone defects are often treated with recombinant human BMP-2. Although enhanced bone tissue formation is… read more here.
Keywords: tissue patterning; bmp; bone defect; critical sized ... See more keywords
Self-reinforced piezoelectric chip for scaffold-free repair of critical-sized bone defects
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DOI: 10.1038/s41467-025-61243-w
Abstract: The use of piezoelectric materials to treat critical-sized bone defects typically requires additional stimulation to generate their piezoelectric properties and the implantation of scaffolds to promote bone repair. Here we present a self-reinforced piezoelectric chip… read more here.
Keywords: bone defects; repair; sized bone; chip ... See more keywords
Convergence of scaffold-guided bone regeneration and RIA bone grafting for the treatment of a critical-sized bone defect of the femoral shaft
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Medical Research"
DOI: 10.1186/s40001-020-00471-w
Abstract: Background Critical-sized bone defects, mainly from trauma, infection or tumor resection are a challenging condition, often resulting in prolonged, complicated course of treatment. Autografts are considered as the gold standard to replace lost bone. However,… read more here.
Keywords: femoral shaft; mpcl tcp; treatment; critical sized ... See more keywords
The 3D-Printed Ordered Bredigite Scaffold Promotes Pro-Healing of Critical-Sized Bone Defects by Regulating Macrophage Polarization
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s393080
Abstract: Background Repairing critical-sized bone defects secondary to traumatic or tumorous damage is a complex conundrum in clinical practice; in this case, artificial scaffolds exhibited preferable outcomes. Bredigite (BRT, Ca7MgSi4O16) bioceramic possesses excellent physicochemical properties and… read more here.
Keywords: sized bone; bone; critical sized; macrophage ... See more keywords
3D-Printing for Critical Sized Bone Defects: Current Concepts and Future Directions
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineering"
DOI: 10.3390/bioengineering9110680
Abstract: The management and definitive treatment of segmental bone defects in the setting of acute trauma, fracture non-union, revision joint arthroplasty, and tumor surgery are challenging clinical problems with no consistently satisfactory solution. Orthopaedic surgeons are… read more here.
Keywords: sized bone; bone; critical sized; printing critical ... See more keywords