Abstract 1742: Dual inhibitor of immunokinase and pan-RAF for the treatment of KRAS-mutated cancers
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DOI: 10.1158/1538-7445.am2018-1742
Abstract: Tumor-associated macrophages (TAMs) represent most of the white blood cell population in solid tumors. TAMs usually display an M2-like phenotype due to signals from the tumor microenvironment, such as IL-10, VEGFA and CSF-1/M-CSF. These anti-inflammatory… read more here.
Keywords: inhibitor; sjp 1601; treatment; cancer ... See more keywords