Genetics and Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis: What Have We Learned?
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DOI: 10.1001/jamaophthalmol.2017.0136
Abstract: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are part of a spectrum of severe cutaneous reactions affecting skin and mucous membranes.1 Affected patients usually develop a prodrome of fever and malaise, followed by the… read more here.
Keywords: sjs ten; genetics; johnson syndrome; sjs ... See more keywords
A cross-sectional comparative study on chronic ocular manifestations of Stevens–Johnson syndrome and toxic epidermal necrolysis in Chinese eyes: a 15-year case series
Sign Up to like & getrecommendations! Published in 2017 at "International Ophthalmology"
DOI: 10.1007/s10792-017-0576-5
Abstract: PurposeTo compare the chronic ocular manifestations in Stevens–Johnson syndrome and toxic epidermal necrolysis patients from a 15-year cohort.MethodsAll SJS and TEN patients admitted to our burn intensive care unit between 1999 and 2014 were invited… read more here.
Keywords: sjs ten; manifestations stevens; ocular manifestations; sjs ... See more keywords
Is acetaminophen associated with a risk of Stevens–Johnson syndrome and toxic epidermal necrolysis? Analysis of the French Pharmacovigilance Database
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Clinical Pharmacology"
DOI: 10.1111/bcp.13445
Abstract: AIM Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but severe mostly drug-induced cutaneous reactions. Acetaminophen is an over-the-counter drug used worldwide to treat pain and reduce fever. In 2013, the US Food… read more here.
Keywords: sjs ten; french pharmacovigilance; sjs; drug ... See more keywords
Levamisole induced toxic epidermal necrolysis: A case report
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DOI: 10.1111/bcp.14533
Abstract: Stevens‐Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life‐threatening immune‐mediated hypersensitivity reactions. Various drugs, such as Non Steroidal Anti‐inflammatory drugs (NSAIDS), allopurinol, anticonvulsants and antibiotics, have been implicated as triggering agent of SJS/TEN. Levamisole… read more here.
Keywords: levamisole; sjs; epidermal necrolysis; levamisole induced ... See more keywords
Long‐term complications of Stevens–Johnson syndrome/toxic epidermal necrolysis (SJS/TEN): the spectrum of chronic problems in patients who survive an episode of SJS/TEN necessitates multidisciplinary follow‐up
Sign Up to like & getrecommendations! Published in 2017 at "British Journal of Dermatology"
DOI: 10.1111/bjd.15360
Abstract: Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe adverse reactions to drugs that cause a life‐threatening eruption of mucocutaneous blistering and epithelial sloughing. While the acute complications of SJS/TEN are well described, it… read more here.
Keywords: sjs ten; stevens johnson; sjs; epidermal necrolysis ... See more keywords
SAT0215 HISTORY OF TONSILLECTOMY IS ASSOCIATED WITH GLANDULAR INFLAMMATION IN SJÖGREN’S SYNDROME
Sign Up to like & getrecommendations! Published in 2020 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2020-eular.2112
Abstract: The palatine tonsils are secondary lymphoid-organs that serve as the first line of defense against pathogens. Whether history of tonsillectomy (TE) is associated with the phenotype of Sjögren`s syndrome (SjS) has not been investigated to… read more here.
Keywords: none declared; sjs; sjs patients; gren syndrome ... See more keywords
AB0396 DIAGNOSTIC PROTOCOL INCLUDING MINIMALLY INVASIVE MINOR SALIVARY GLANDS BIOPSY IN SJÖGREN’S SYNDROME IN A SPANISH REFERENCE CENTER
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DOI: 10.1136/annrheumdis-2020-eular.4921
Abstract: Background: Sjogren’s syndrome (SjS) is a systemic autoimmune disease with a broad clinical presentation from dry syndrome to systemic extraglandular manifestations. The diagnosis can be complex since none of the markers, except anti-Ro, is sufficiently… read more here.
Keywords: dry syndrome; diagnostic protocol; sjs; msgb ... See more keywords
Sjögren’s and non-Sjögren’s sicca share a similar symptom burden but with a distinct symptom-associated proteomic signature
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DOI: 10.1136/rmdopen-2021-002119
Abstract: Objectives Given the similarity in symptoms between primary Sjogren’s syndrome (SjS) and non-SjS sicca syndrome (sicca), we sought to characterise clinical and proteomic predictors of symptoms in both groups in order to better understand disease… read more here.
Keywords: symptom burden; sjs sicca; gren non; sjs ... See more keywords
Capecitabine induced Steven–Johnson syndrome: A rare case report
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DOI: 10.1177/10781552211027945
Abstract: Introduction Steven–Johnson syndrome (SJS) is a serious mucocutaneous reaction, characterized by fever, influenza-like symptoms and followed by dermatological manifestations. Capecitabine is an oral fluoropyrimidine carbamate analogue of 5-Fluorouracil (5-FU). It is widely accepted for many… read more here.
Keywords: steven johnson; johnson syndrome; sjs; capecitabine ... See more keywords
Matrix metalloproteinase 9 is associated with conjunctival microbiota culture positivity in Korean patients with chronic Stevens-Johnson syndrome
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DOI: 10.1186/s12886-022-02406-x
Abstract: Background Stevens-Johnson syndrome (SJS) is an abnormal immune-response causing extensive exfoliation of the mucocutaneous tissue including conjunctiva. While several factors are associated with the alteration of conjunctival microbiota, the conjunctiva of SJS patients are found… read more here.
Keywords: johnson syndrome; sjs; conjunctival microbiota; positivity ... See more keywords
Life-threatening dermatoses: Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis. Impact on the Spanish public health system (2010-2015)
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DOI: 10.1371/journal.pone.0198582
Abstract: Background Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are serious mucocutaneous reactions. In Spain, the epidemiology and resulting expenses of these diseases are not well established. Methodology Retrospective descriptive study using the Minimum Basic… read more here.
Keywords: system; johnson syndrome; sjs; epidermal necrolysis ... See more keywords